X-CEFF ( POWDER, INJECTION ) ( 1 g )

Manufacturer
Lupin Laboratories (Lupinova)
Drug Type
 Branded Drug
Medicine System
 Allopathy
Drug Availability
 Pharmacy (P)

Ingredients

SKU

Brand NameDosage Form PackQty per PackInquiry
X-CEFFPOWDER, INJECTION1 Please Inquire

Related Generic Drugs

Related Monographs

Cefotaxime

Pregnancy Category B

Essential Medicine :

Schedule Drug Category: H

Usage / Indications

Infections due to sensitive Gram positive and Gram negative bacteria such as bacteraemia, cellulites, intra-abdominal infections, gonorrhoea, bone or joint infections, skin and skin structure infections, urinary tract infections, septicaemias, surgical prophylaxis, endometritis, life threatening resistant/hospital acquired infections, infections in immunocompromised patients, Haemophilus epiglottitis and meningitis.

Dosage

Source : IAP Pediatric Drug Formulary
Newborn (severe infections like meningitis) 50 mg/kg/dose - <7 day 2 times, 7-21 day 3 times, 21-30 days 3-4 times. 1 month - 12yr 50 mg/kg/dose and 12-18 yr 1-3gm 2 times daily. Dosage adjustment in renal impairment Due to extra-renal elimination it is only necessary to reduce dose in severe renal impairment (creatinine clearance ,10ml/minute/1.73qm). A normal single dose should be given as a loading dose then the daily dose should be halved without a change in frequency

Source : NFI National Formulary of India

  • Susceptible infections: 1–2g by i.v or i.m injection, 8 – 12 hourly. Max.-12 g/day. Child- 50-100 mg/kg/day.
  • Surgical prophylaxis: 1g by i.v or i.m injection, 30-90 minutes before procedure.
  • Gonorrhoea: 0.5–1g by i.m injection, as a single dose.
  • Septicaemia, meningitis:Adult- 2g i.v, 6-8 hourly for 14-28 days.
  • Neonates- 50 mg/kg daily in 2–4 divided doses may be increased to 150–200 mg/kg daily in severe infections.
  • Child- 100–150 mg/kg daily in 2–4 divided doses increased up to 200 mg/kg daily in very severe infections.

Contraindications

  • Renal disease
  • Hypersensitivity to cephalosporins.

Precautions

  • Impaired kidney or liver disease, colitis
  • History of penicillin allergy
  • Pregnancy 
  • Lactation
  • Diabetes

Side Effects / Adverse Effects

  • Local inflammation or pain at injection site
  • Thrombocytopenia, eosinophilia, leukopenia
  • Pseudomembranous colitis, moniliasis, diarrhoea, candidiasis, decreased urination
  • Seizures, headache, nausea and vomiting
  • Jaundice
  • Steven’s Johnson syndrome

Storage

Store protected from light at a temperature not exceeding 30⁰C

Disclaimer:

Every effort has been made to ensure that the information provided by HealthKonnect is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource.This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. HealthKonnect India Pvt Ltd does not assume any responsibility for any aspect of healthcare administered with the aid of information HealthKonnect provides.The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor or pharmacist.

The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including local taxes. These are only approximate indicative prices of the drug.
Loading ...