JACIMOX ( SYRUP, DRY )

• Urinary-tract infections, upper respiratory tract infections, bronchitis
• Pneumonia
• Otitis media
• Dental abscess
• Osteomyelitis
• Lyme disease in children
• Endocarditis prophylaxis
• Post-splenectomy prophylaxis
• Gynaecological infections
• Gonorrhoea
• Helicobacter pylori eradication

Source : IAP Pediatric Drug Formulary
Oral  20-50mg/kg/day in 2 or 3 divided doses. Higher dose of 80-90mg/kg in acute suppurative otitis media. (maximum of 500 mg 2-3 times daily). In uncomplicated gonorrhoea - 3gm with 1gm probenecid.

Source : NFI National Formulary of India
Oral  Adult- 250 mg every 8 h, double in severe Infection.

Otitis media: 1g every 8 h. Enteric fever: 2 to 4g daily in divided doses for 14 to 21 days.

Intramuscular injection

500 mg every 8 h.

Intravenous injection or infusion

500 mg every 8 h, increase to 1g every 6 h in case of severe infection.

Child up to 10 years- 125 mg every 8 h,double in severe infections.

Otitis media: 40 mg/kg body weight daily in three divided doses.

Enteric fever: 50 to 100 mg/kg body weight in three divided doses for 14 to 21 days.

Intramuscular injection

50 to 100 mg/kg body weight in divided doses. Intravenous injection or infusion 50 to 100 mg/kg body weight in divided doses."

Hypersensitivity to penicillins

• History of allergy
• Renal impairment
• Erythematous rashes common in glandular fever, chronic lymphatic leukaemia and pos- sibly HIV infection
• Lactation 
• Interactions
• possibility of super infection with mycotic patho- gens, mononucleosis, hepatic impairment ,pregnancy

• Nausea and vomiting, diarrhoea
• Rashes (hypersensitivity or toxic response, may be serious reaction-discontinue treatment)
• Hypersensitivity reactions including Steven’s Johnson syndrome, urticaria, angioedema, anaphylaxis, serum sickness-like reactions, haemolytic anaemia, interstitial nephritis
• Rarely, antibiotic-associated colitis
• Neutropenia, thrombocytopenia, coagulation disorders
• Rarely, central nervous system disorders including convulsions associated with high doses or impaired renal function
• Mucocutaneous candidiasis, with discolouration
• Agitation

• Tablet, Capsule and Oral suspension: Store protected from moisture at a temperature not exceeding 30°C. 
• Injection: Store protected from moisture in a sterile, tamper evident container sealed so as to exclude micro-organisms at temperature not exceeding 30°C.