Pregnancy Category C
Essential Medicine :
Schedule Drug Category: H
Source : IAP Pediatric Drug Formulary
Oral < 12 yr initially 0.7mg.kg and increased to 3mg/kg/day and 12-18 yr 20-40 mg initially as single dose and at higher doses in 2 divided doses. H Pvlori - Oral 1-12 yr 1-2mg/kg rounded to nearest 10mg and max 40mg and in 12-18 yr 40 mg as single dose for 14 days with amoxcillin and clarithromycin or amoxicillin and metronidazole or clarithromycin and metronidazole.
Source : NFI National Formulary of India
Oral: Benign gastric and duodenal ulcers: 20 mg once a day for 4 weeks in duodenal ulcers, for 8 weeks in gastric ulcers, Increase to 40 mg in severe case. Maintenance for recurrent duodenal ulcers: 20 mg once daily. Prevention of relapse: 10 mg daily. NSAIDs associated gastric or duodenal ulcers or gastro-duodenal erosions: 20 mg daily for 4 weeks. Prophylaxis in case of history associated with gastric/duodenal ulcers or dyspepsia: 20 mg daily. Zollinger-Ellison syndrome: 60 mg to 120 mg/day or more, into divided doses. Gastric acid reduction during gastric surgery: 40 mg on preceding evening then 40 mg 2 to 6 h before surgery.
Hypersensitivity.
Nausea, abdominal pain, constipation, flatulence, diarrhoea, headache, skin rashes, subacute, myopathy, arthralgias, increased risk of hip fractures, decreased B12 absorption, hypergastrenemia, respiratory and Clostridium difficile infections, hepatic dysfunction.
Store protected from light and moisture at a temperature not exceeding 300C.
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